The Chalerm Phrakiart police station was alerted at 4.10am of the accident on the Bangkok-bound Phaholyothin road in Moo 9 village of Tambon Huay Bong.
Police said the driver along with eight other passengers were injured and rushed to Saraburi Hospital.
An unidentified passenger was hurled out of the van by the impact and killed instantly.
Two passengers died inside the van and were identified as Jariya Sae-heng, 61, and Porsianghai Sae-ugng, 65.
Police quoted the survivors as saying that the van was transporting a Chinese Opera troupe back from their show in Phetchabun’s Lomsak district back to Bangkok when the accident occurred.